Our Pipeline
We are programming biology to create optimal therapeutics for the greatest impact on human health.
| Program | Target | Indication | Phase | Collaborations | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Generating | IND Enabling | Phase 1 | Phase 2 | Phase 3 | ||||||||
| Immunology | ||||||||||||
| GB-0895 | TSLP | Severe Asthma |
Phase Phase 1 Completed |
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| GB-0895 | TSLP | COPD |
Phase Phase 1 |
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| GB-7624 | IL-13 | Atopic Dermatitis |
Phase Phase 1 |
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| Bispecific | TSLP x IL-13 | Atopic Dermatitis |
Phase Generating |
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| GB-6537 | TL1A | Ulcerative Colitis |
Phase IND Enabling |
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| GB-4558 | OX40L | Atopic Dermatitis |
Phase IND Enabling |
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| Bispecific | TL1A x IL-23 | Ulcerative Colitis |
Phase Generating |
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| Oncology | ||||||||||||
| GB-5267 | Undisclosed | Advanced Solid Tumors |
Phase IND Enabling |
Collaborations
50/50
|
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| Bispecific | Undisclosed | NSCLC |
Phase Generating |
Collaborations
The University of Texas
MD Anderson Cancer Center 50/50 |
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| GB-4362 | Free MMAE | ADC Toxin Neutralizer |
Phase IND Enabling |
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| Infectious Disease | ||||||||||||
| GB-0669* | SARS-CoV-2 S2 | Covid-19 |
Phase Phase 1 Completed |
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| Undisclosed | ||||||||||||
| Amgen |
6 Undisclosed Programs
|
Collaborations
|
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| Novartis |
Multiple Undisclosed Programs
|
Collaborations
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*Deprioritized for internal development |
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Currently, participation in clinical trials is the only way for patients to gain access to Generate:Biomedicines’ investigational therapies. As more clinical data on the safety and efficacy of these investigational therapies become available, we will review and update our policy on Expanded Access.