Our Pipeline
We are programming biology to create optimal therapeutics for the greatest impact on human health.
| Program | Lead Indication | Target | Generating | IND-enabling | Phase 1 | Collaborations | ||
|---|---|---|---|---|---|---|---|---|
| Immunology | ||||||||
| GB-0895 | Severe Asthma | TSLP |
Phase 1 |
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| GB-7624 | Atopic Dermatitis | IL-13 |
Phase: IND-enabling |
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| Coform and bispecific | Severe Asthma | TSLP x IL-13 |
Phase: IND-enabling |
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| mAb | Ulcerative Colitis | TL1A |
Phase: Generating |
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| mAb | Atopic Dermatitis | OX40L |
Phase: Generating |
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| Bispecific | Ulcerative Colitis | TL1A x IL-23 |
Phase: Generating |
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| Mono and combo incl. bsAb |
Various |
Phase: Generating |
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| Immuno-oncology | ||||||||
| Armored CAR-T | Advanced Solid Tumors | Undisclosed |
Phase: IND-enabling |
50/50
|
||||
| Bispecific | NSCLC | Undisclosed |
Phase: Generating |
The University of Texas
MD Anderson Cancer Center 50/50 |
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| ADCs | ||||||||
| Protein Binder | ADC Toxin Neutralizer | Free MMAE |
Phase: IND-enabling |
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| ADC | Advanced Solid Tumors | Undisclosed |
Phase: Generating |
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| Infectious Disease | ||||||||
| GB-0669 | Covid-19 | SARS-CoV-2 S2 |
Phase 1 Completed |
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| mAb | Covid-19 | SARS-CoV-2 RBD cl.IV |
Phase: IND-enabling |
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| Undisclosed | ||||||||
| Amgen |
6 Undisclosed Programs
|
 |
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| Novartis |
Multiple Undisclosed Programs
|
 |
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Policy on Expanded Access (EA) to Investigational Drugs
Currently, participation in clinical trials is the only way for patients to gain access to Generate:Biomedicines’ investigational therapies. As more clinical data on the safety and efficacy of these investigational therapies become available, we will review and update our policy on Expanded Access.