Our Pipeline
We are programming biology to create optimal therapeutics for the greatest impact on human health.
Program | Target | Indication | Generating | IND-enabling | Phase 1 | Collaborations | ||
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Immunology | ||||||||
GB-0895 | TSLP | Severe Asthma |
Phase Phase 1 |
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GB-0895 | TSLP | COPD |
Phase Phase 1 |
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GB-7624 | IL-13 | Atopic Dermatitis |
Phase Phase 1 |
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Coform and bispecific | TSLP x IL-13 | Severe Asthma |
Phase IND-enabling |
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mAb | TL1A | Ulcerative Colitis |
Phase Generating |
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mAb | OX40L | Atopic Dermatitis |
Phase Generating |
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Bispecific | TL1A x IL-23 | Ulcerative Colitis |
Phase Generating |
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Mono and combo incl. bsAb |
Various |
Phase Generating |
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Immuno-oncology | ||||||||
Armored CAR-T | Undisclosed | Advanced Solid Tumors |
Phase IND-enabling |
Collaborations ![]() |
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Bispecific | Undisclosed | NSCLC |
Phase Generating |
Collaborations
The University of Texas
MD Anderson Cancer Center 50/50 |
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ADCs | ||||||||
Protein Binder | Free MMAE | ADC Toxin Neutralizer |
Phase IND-enabling |
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ADC | Undisclosed | Advanced Solid Tumors |
Phase Generating |
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Infectious Disease | ||||||||
GB-0669* | SARS-CoV-2 S2 | Covid-19 |
Phase Phase 1 |
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mAb* | SARS-CoV-2 RBD cl.IV | Covid-19 |
Phase IND-enabling |
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Undisclosed | ||||||||
Amgen |
6 Undisclosed Programs
|
Collaborations ![]() |
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Novartis |
Multiple Undisclosed Programs
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Collaborations ![]() |
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*Deprioritized for internal development |
Currently, participation in clinical trials is the only way for patients to gain access to Generate:Biomedicines’ investigational therapies. As more clinical data on the safety and efficacy of these investigational therapies become available, we will review and update our policy on Expanded Access.